Swiss drugs firm Roche was the original inventor of Roaccutane's active ingredient Isotretinoin which was developed to provide acne sufferers with an effective treatment that could provide symptomatic relief quickly. Although the exact mechanism by which Roaccutane works is not fully known, one study showed it amplified production of NDAL which in turn reduces sebum production while also exhibiting an antimicrobial effect.
As the original form of the active ingredient Isotretinoin, Roaccutane remains most patients favoured form of the drug due to the greater assurance provided by knowing you are taking the Roche version. Roaccutane is considered to be a stronger option for treating acne, working where other treatments fail.
Roaccutane is used for treating those with severe acne but increasingly over the years, its use has been extended to those with milder forms of acne and even to those with conditions not related to acne at all such as other skin conditions and genital warts.
Roaccutane dosing is typically once a day but there may be adjustments made based on the assessment of the physician in charge of a patient's treatment. Always refer to product literature.