Rasagiline is a potent, selective, irreversible monoamine oxidase (MAO) type-B inhibitor. It is a useful agent in the symptomatic treatment of Parkinson's disease. Rasagiline can be used both on its own in early Parkinson's disease, and as an adjunct to levodopa (L-DOPA) treatment in later stages of the disorder, where it is beneficial against end-of-dose fluctuations in motor function. There is tentative evidence that rasagiline can slow the progression of Parkinson's disease itself as well as offer symptomatic relief.
Rasagiline and its analogues are under investigation for Alzheimer's disease. They apparently enhance memory and learning. Rasagiline may also improve mood, motivation and age-related memory decline in the ageing but nominally well adult population.
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Only those patient that have been advised to take this medication by their clinician
Rasagiline can be taken orally, with or without food. Typical dosage is 1 mg per day. Absorption is rapid; peak plasma concentration is reached after around 30 minutes. Always refer to product literature
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